Category Archives: Uncategorized

I Dr. Googled Why My Muscles Won’t Cooperate Anymore

Uncategorized

If you’ve ever known anyone with ALS, it’s heart-breaking to watch.

One day they’re walking, cooking, doing yard work, and living a normal life. 

Next day, you watch as they keep tripping over the edge of the carpet… 

…can hardly make it through a meal without coughing……and their fingers refuse to close around a mug handle for a simple sip of coffee.

Every 90 Minutes Someone Gets the News…

Some catch it early. 

Most, like Paul, catch it in their 60s. 

“My wrist hurts when I twirl it around. I get tremors. Body twitching.”

“What bothers me the most is my face. My tongue won’t cooperate anymore. And my words are so slurred, my wife can’t understand me half the time. It’s insanely frustrating!”

And he knows it will only get worse.

His family dreaded the day in the future when Paul would likely not be able to walk or even breathe.

152 years after its discovery, ALS continues to strike without warning [3]. Every year, ALS turns the lives of 6,000 Americans into a living nightmare. [2]

It’s Like the Body Stops Listening To the Brain’s Command

While scientists can’t yet pinpoint why some people get ALS, they know the downward spiral is caused by nerve damage… 

Damage that chips away at the lining of a special type of nerve; motor neurons.

Think of motor neurons like the wiring that connects lights in your living room to a switch. Normally, you flip the switch, and all the lights go on. 

The problem is… once ALS shows up on the scene, these wires start to erode and deteriorate. 

One day you walk into your living room and flip the switch, expecting brightness. 

This time, only half the lights illuminate. 

The other light bulbs are still there. 

But they remain dark. Those wires failed.

They never heard the command to turn on. 

A similar thing happens to the motor neurons connecting the brain to the spinal cord of an ALS patient.

Once ALS shows up on the scene, these wires (motor neurons) start to erode and deteriorate.

It’s a tidal wave that forces more neurons off the grid. They lose their ability to talk to muscles in the arms, legs, chest, throat and mouth.

It’s like the brain keeps talking in a language the muscles can no longer understand.  

If you or your loved one has ALS, this is when they need help dressing and showering. 

Others may notice one arm losing strength. 

The sad truth is… 4 out of 5 people with ALS are likely to suffer asymmetric limb weakness. [1]

One side of the body works. The other side grows frail and atrophies.And while scientists have yet to figure a clear-cut treatment… 

Here’s a Ray of Sunshine in a Dark Sky

In this special report, I’m going to show you a breakthrough protocol… that uses nutrients found naturally in the body… to help 7 out of every 10 people who try it. [8]

That’s not all…

…while you’d expect everybody to respond differently, more than half the people who follow this methodology report elevated energy levels and…73% report a reduction in muscle tremors. [8]

Uses nutrients found naturally in the body to supports energy levels and soothe away muscle weakness.

What makes this protocol work is, it takes a different approach:

Instead of focusing on the symptoms, it helps brain nerves survive the ALS toxic tsunami wave.

What’s the toxic tsunami wave?

Well, scientists have long known this is one of the first red flags that… flips the environment of surrounding brain nerves to go from livable to a living hell.

Case in point, it only takes 24 hours for this destructive cocktail to start deteriorating brain neurons. [6]

And this is important because, the deterioration (and death) of these neurons is the reason why ALS patients start feeling their muscles weaken and ultimately become paralyzed.

What Spanish Scientists Discovered While Saving Neurons of Stroke Survivors That May Help Those With ALS

A few years ago, a team of Spanish scientists set out to figure the best way to save the most brain nerves after someone had a stroke. [6]

This is especially challenging because, the worst hit area (the core zone) suffers an extreme drop in blood flow. As you’d expect, this leaves brain nerves without oxygen and glucose. 

In short, leaving brain nerves with no way to produce energy. 

The longer this goes on, the more brain neurons perish.

No energy, no life. Remember that.

The Spanish scientists witnessed another phenomenon that accelerates the death of neurons.

  • In a healthy brain, glutamate is a friend. This essential amino acid helps neurons talk to each other. It also helps us with memory and learning. 
  • When someone suffers a stroke, glutamate is a foe. It’s bad news because glutamate levels in the brain spike to 10 times normal levels, contributing to the deterioration of the brain… [6]

Triggering a Toxic Tsunami That Kills Brain Neurons

The rising glutamate is like an accelerating tidal wave:

Glutamate shoots up to levels the body can’t handle.

As you already know, this pushes motor neurons to deteriorate and die.

As these cells die, they burst, releasing more glutamate into the system.

This in turn, elevates glutamate levels even higher, affecting more neighboring cells.

You can probably guess what happens to those neighboring cells? They too die and burst, releasing more glutamate.

And so on and so on until the body is flooded with toxic levels of glutamate. It’s a vicious downward spiral.

When neurons die they burst releasing more glutamate into the system.

When there is a flood of glutamate in our brains, it’s almost as if the wiring stops connecting with the rest of the body, like in our light switch example.  

Just like with stroke victims, we believe the same phenomenon of unplugging the brain communicator cells from the rest of the body is at play when it comes to ALS.

So What Can You Do About It?

Many people suffer needlessly because they don’t know their options.

For example, you might think that the most effective approach is pressing the brakes on that glutamate ‘toxic tsunami.’

Afterall, that’s the approach used by one of the more popular solutions for ALS [1].

What kind of relief does it offer?

Only a median increased survival time of about two to three months.

What’s more, England’s National Health Service reports that patients who use it… ‘feel no different day-to-day.’ [10]

And while we always recommend consulting your physician on what would help you the most, we suspect you’re here for a reason…

…you want to leave no stone unturned because:

While we don’t know how many tomorrows we’ll have… 

We Can’t Sit and Watch as Our Loved Ones Fade Away

That’s why, back in 2014, we decided to take a different approach to helping ALS patients live a better life.

Remember how the Spanish scientists discovered one reason that triggers neurons to perish is… they are left with no way to produce energy?

No energy. No life.

So, what’s the battery that energizes our cells?

It’s the mitochondria. When you build up the strength of this powerhouse, it can withstand the onslaught of glutamate.

So, instead of trying to stop the glutamate ‘toxic tsunami’ wave by changing the cell’s environment (as other popular solutions do), we’re arming neurons to survive that brutal toxic wave war.

The result is Simplesa’s AAKG+ core protocol blend.

AAKG+ is an advanced, four-in-one nutritional solution that’s purposely designed to help alter the course of ALS.

And it does this by fueling the cellular energy cycle. This, in turn, kicks the mitochondria’s ‘energy production capacity’ into high gear.

New energy. New life.

This novel approach focuses on arming the mitochondria so it can withstand the onslaught of toxic glutamate.

With consistent use, Simplesa’s AAKG+ helps ease muscle twitching, relieve body weakness and support elevated energy levels.

And while everyone responds differently, it’s not uncommon to hear comments like this one from Jennifer:

“It gives me the energy to stay up all day, like from 7 am to midnight.”

In a moment, you’ll get to hear 100 more reviews to help you decide if AAKG+ is right for you or your loved one. 

First, let’s cover the 4 potent ingredients that make AAKG+ work. 

The 4 neuro-nutrients are meticulously sourced and scientifically formulated right here in the USA… to ensure the highest absorption rates and uncompromising quality.

It starts with…

#1) The Key to Replenishing Our Cellular Battery

Alpha-Ketoglutarate (AKG) is a natural substance that’s concentrated in the cell’s mitochondria (the battery that energizes our cells) and the liquid gel which fills our cells. 

AKG isn’t just a potent antioxidant, that also increases collagen production [11], it also plays a much bigger role:

It regulates the speed of cellular energy production.

Case in point, draining the levels of AKG in our cells is like pressing the breaks on the cell’s ability to produce energy.

And this happens because AKG works as an ‘energy donor’ in the Krebs cycle.

You may remember the Krebs cycle from science or biology class. Without getting too technical, the Krebs cycle is an 8-step chain reaction happening inside our mitochondria. 

End result? Energy that powers all living cells.

Here’s where it gets interesting…

Scientists have long known that the cell’s energy production rate is linked to how fast we age. The lower our cellular energy is, the faster we age. [19]

So, researchers at the Buck Institute wanted to figure the impact of consuming AKG. [12, 13] 

Could it put the usual signs of cell aging on time-out?

In the study, researchers divided 182 aging mice (55 years in human years) into two groups. Only one group of mice was fed a diet containing AKG. 

Then, every 8 weeks the researchers would measure for signs of vitality and zest for life (such as eye health, tremors, grip strength, and curving of the spine among other signs of aging). This went on for 21 months, or for as long as mice were alive.

The result: the group that consumed AKG saw a 40% boost in healthspan.

What’s healthspan? 

It’s not merely surviving as the years go by. It’s enjoying blissful days, free of the usual alignments and disabilities that come with age.

Walking, breathing, living and having a zest for life. 

For those reasons, AKG is the key superstar ingredient we’ve included in Simplesa’s AAKG+. 

It also includes…

#2) COQ10 to Shield Against Neuron Damage

You may have heard of CoQ10 and how it’s among nature’s most powerful antioxidants.

But did you know it’s more effective than vitamin E when it comes to protecting against cell neuron damage. [14]

And, neuron damage is one of the main reasons the brain communicator cells lose their ability to talk to the rest of the body. 

In fact, studies show that CoQ10 might play a bigger role than we once thought when it comes to… helping turn around nerve damage (like ALS). [15] [16]

CoQ10 more effective than vitamin E when it comes to protecting against cell neuron damage.

But that’s only part of the CoQ10 story.

It’s no coincidence that CoQ10 lives in the cell’s mitochondria (our energy powerhouse). 

You see, CoQ10 isn’t just essential for helping the body patch up repair damaged cells, it’s also the spark your cells need to generate energy.

Just like AKG, it plays a crucial role in amplifying the cell’s energy production rate (the Krebs cycle).

Are you starting to see how CoQ10 plays two critical roles when it comes to ALS?

  • On one level, it helps protect the mitochondria from damage (the potent antioxidant effect). 
  • While, at the same time, it boosts the mitochondria’s ability to produce energy. Energy it needs to survive the glutamate ‘toxic tsunami.’

For those reasons, we’ve included the most bioavailable form of CoQ10 in Simplesa’s AAKG+. But that’s not all, AAKG+ has one more ingredient that…

#3) Helps Squash The Toxic Tidal Wave

GABA (Gamma Aminobutyric Acid) is a chemical messenger in the brain. It has a calming effect. 

Our body needs this to make it through stress and anxiety – without crushing our nervous system. 

Simply put, it shields our nerve cells from being over-stimulated (stressed out).

Why is this important when it comes to ALS?

In healthy adults there’s a balance between GABA and glutamate. 

The first calms our nerves, the second excites them. It’s like an on and off switch.

But what happens if the switch is always on?

Like a morning alarm clock that buzzes forever. No rest. 

We suspect that’s what’s happening to the brain cells of someone with ALS. In fact, studies show that GABA levels diminish and dip as glutamate levels spike. [17] 

Sounds familiar? This is the glutamate ‘toxic tsunami’ wave pushing neurons to the edge of existence. 

There’s two more reasons for including GABA in AAKG+. 

  • Firstly, we want to replenish the body’s GABA stores – because low levels of GABA contribute to muscle spasticity and stiffness.
  • And, secondly, GABA pushes back on the excessive glutamate levels… giving neurons a fighting chance against the toxic tidal wave. 

Knowing that, we did extensive research to identify the most effective approach to…

#4) Help Brain Neurons Survive and Regrow

Niacin is a water-soluble B vitamin. Once in the body, it’s converted into the second most important coenzyme in the body; NAD (nicotinamide adenine dinucleotide).

Why is it so important?

Because it’s one of only a few coenzymes that directly impact the body’s ability to create and utilize energy.

In fact, supplementing with NAD has been shown to bump up the mitochondria’s ‘energy production capacity.’ [18]

What’s more, mental agility is often a sign of sufficient NAD levels in nerve cells.  Why? Because it plays a key role in brain neuron development and survival.

Naturally, scientists wanted to put this to the test in the most extreme of conditions; stroke survivors.

The cell’s inability to regrow axons (wire like structures) hampers the ability to move and feel limbs.

You see, one of reasons a stroke (or spinal cord injury) cripples the person’s ability to move, or even feel their limbs is… the cell’s inability to regrow axons. [21]

What are axons? Simply put, it’s the thin ‘wire like’ structure of the neuron that helps it communicate with other neurons. 

So, here’s what scientists at Oakland University did: 

They simulated a stroke in lab rats by blocking blood flow to the brain for two hours. Then, they separated the rats into two groups. One group was fed a daily dose of niacin for 14 days. [20]

Scientists were amazed by the results: niacin plays a major role in supporting the nerve’s regeneration process (neurite outgrowth). 

Can you see how this is relevant to ALS?

Case in point, scientists believe this nerve regeneration (neurite outgrowth) process is a critical factor in restoring neuron function after it’s damaged. [22] 

By now, you can probably see why we’ve included Alpha-Ketoglutarate (AKG), GABA, Ubiquinol (CoQ10) and Niacin in Simplesa’s AAKG+ Core Powder.The 4 neuro-nutrients in AAKG+ aren’t just 100% natural, they’re also…

The Purest Form, Potent Compounds to Ensure the Highest Bioavailability and Purity

What this means is… we’ve gone to extreme lengths to source these 4 neuro-nutrients are in the purest, freshest and most effective form.

The same raw form supported by scientific research. (You can see the certificates of analysis right here.)

No fillers. No cutting corners because our client’s wellbeing depends on it. 

It’s been our pledge since starting back in 2014; quality first.

That’s why, Simplesa’s AAKG+ is scientifically formulated and manufactured in the USA in an FDA inspected facility.

What’s more, the 4 neuro-nutrients in AAKG+ aren’t just designed to work in synergy… where the combined effect is far greater than taking each nutrient on its own…  Simplesa’s AAKG+ is purposely designed to…

  • Soothe away muscle discomfort and weakness. Instead of watching muscles waste away this helps your body get stronger.
  • Increase mitochondrial energy output to help give you the energy you need to live life.
  • Reduce anxious feelings and negative moods (start feeling like your normal self again).
  • Sooth away muscle fatigue, leg cramps and muscle twitching that makes holding a cup of coffee near impossible.
  • The most bioavailable form of CoQ10 (Ubiquinol) helps give further protection against cell neuron damage.

Thousands of men and women swear it helps slow down progression and improve their quality of life. And now, you can too.

How Much of a Difference Can AAKG+ Make?

Just ask Scot , Sarah, Ronnie and others…

And while I can’t promise a magic carpet ride (because everybody’s different), here’s how it’s been changing lives since 2014:

Real results from real ALS patients since 2014 (there are 100s more reviews to see here.

If you’ve read this far, I think you can see why…

You Too Can Benefit From AAKG+

We also made sure it’s not another stack of ‘hard to swallow’ pills. 

Instead. it’s super simple to use:

  1. Simply add 1 leveled scoop to any beverage or food with a consistency that permits easy mixing. 
  2. Stir until thoroughly mixed. (It tastes good and mixes well and easily with a shaker bottle.)
  3. Take three times daily or as directed by your health care practitioner.

As you’d expect, Simplesa’s AAKG+ has clearly spelled out ingredients (no mystery blend that leaves you wondering what’s in the mix):

Now, it’s perfectly normal to realize that… the only way to help you decide if AAKG+ is right for you or your loved one, is getting it into your hands (so you can start using it and noticing the difference it makes).

For that reason, we’ve done 3 things:

Firstly, you pay zero for shipping and handling.

Since AAKG+ isn’t available in health food stores, we’re eating the cost of shipping to get it into your hands as soon as possible (and let it start working for you or your loved one right away). 

Secondly, you risk nothing by trying AAKG+ today.

All we ask is that you use it for 30 days. If, at any point in the next 90 days, you’re not satisfied with for any reason (or no reason at all), then return the empty bottles for a full, courteous refund.

Thirdly, because the results have been so positive, we’re trying to get it into the hands of more people who need relief now.

That’s why, for a limited time, you can take advantage of this exclusive offer…

Try AAKG+ Risk-Free at the Lowest Price and Get a Free Gift

If you tried to purchase just 2 of the 4 neuro-nutrients in AAKG+ at your local health food store… getting a 30-day supply of CoQ10 (Ubiquinol) and high-dose  AKG… you could easily spend up to $318.5.

And you’d have no guarantee you’d get these neuro-nutrients in the most effective pure form compounds to ensure the highest bioavailability. 

But thanks to this special offer, you can get all 4 neuro-nutrients in one convenient, easy to use solution (instead of having to mix and match what might be ‘hard to swallow’ pills)… for as little as $4.99 per day.

That could save you as much as $168.51 per month.

Here’s the best part, if you decide to go for the 60-day supply today…

You’ll Get 2 Free AAKG Powder Tubs (Worth $51.98)

Here’s why this is the perfect companion to Simplesa’s AAKG+… 

As you already know, we’ve included Arginine Alpha-Ketoglutarate (AAKG), GABA, Ubiquinol (CoQ10) and Niacin in Simplesa’s AAKG+ Core Powder. 

3 of the neuro-nutrients (GABA, CoQ10 and Niacin) are in full dosages. The fourth neuro-nutrients (AAKG) is set at the minimum recommended dosage of 9 grams a day. 

Why is that important?

To allow you to increase your increase AAKG dosage up to the recommended 18 grams per day at your own pace (without having to increase GABA, CoQ10 and Niacin at the same time).

That’s where Simplesa’s AAKG Powder comes in.

  • It’s the same high-potency, pure form amino acid in AAKG+
  • Simplesa’s protocol calls for 3 main servings of AAKG+ per day and…
  • Smaller doses of AAKG throughout the day. 
  • This is intended to support energy production through the day

Normally, you’d have to buy AAKG separately. However, on this page only… you get two complementary AAKG tubs with your 60-day supply. Take advantage of this generous offer today because it won’t be available forever.

Choose Your Package

These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any diseases.

[1] https://www.simplesanutrition.com/content/pdf/DP-White-Paper.pdf 

[2] https://www.simplesanutrition.com/blog/simplesa-aakg-core-powder-nutrients-support-parkinsons-disease/ 

[3] https://www.pharmaceutical-technology.com/analysis/history-of-als/ 

[4] https://als.ca/blogs/dr-richard-bedlacks-quest-als-discovery-truth/ 

[5] https://journals.sagepub.com/doi/10.1177/0271678X15606721 

References

[1] Deanna Protocol Program for ALS: Substantiation and Putative Mechanisms. 2016.

[2] “ALS Incidence and Prevalence Worldwide.” Alstreatment.com, alstreatment.com/amyotrophic-lateral-sclerosis-incidence/.

[3] “Unmet Needs: A Brief History of ALS and Its Sparse Pipeline.” Pharmaceutical Technology, 10 Sept. 2021, www.pharmaceutical-technology.com/analysis/history-of-als/.

[4] Morris, Tom. “Dr. Richard Bedlack’s Quest for ALS Discovery: The Truth Is out There.” ALS Society of Canada, 27 July 2017, als.ca/blogs/dr-richard-bedlacks-quest-als-discovery-truth/. Accessed 3 Jan. 2023.
 
[5] Castillo, José, et al. “A Novel Mechanism of Neuroprotection: Blood Glutamate Grabber.” Journal of Cerebral Blood Flow & Metabolism, vol. 36, no. 2, 2 Oct. 2015, pp. 292–301, 10.1177/0271678×15606721. Accessed 2 Dec. 2022.

[6] “A Novel Mechanism of Neuroprotection: Blood Glutamate Grabber.” Journal of Cerebral Blood Flow & Metabolism, vol. 36, no. 2, 2 Oct. 2015, pp. 292–301, 10.1177/0271678×15606721. Accessed 2 Dec. 2022.

[7] “Should I Take Riluzole? – Oxford MND Centre.” Www.ouh.nhs.uk, www.ouh.nhs.uk/services/departments/neurosciences/neurology/mnd/support/riluzole.aspx.

[8] “Neuro-Health Protocol : Simplesa : ALS.” Www.simplesanutrition.com, www.simplesanutrition.com/neuro-health/. Accessed 3 Jan. 2023.

[9] Asadi Shahmirzadi, Azar, et al. “Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice.” Cell Metabolism, vol. 32, no. 3, Sept. 2020, pp. 447-456.e6, www.ncbi.nlm.nih.gov/pmc/articles/PMC8508957/, 10.1016/j.cmet.2020.08.004. Accessed 3 Jan. 2023.

[10] “Should I Take Riluzole? – Oxford MND Centre.” Www.ouh.nhs.uk, www.ouh.nhs.uk/services/departments/neurosciences/neurology/mnd/support/riluzole.aspx.

[11] Son, Eui Dong, et al. “Alpha-Ketoglutarate Stimulates Procollagen Production in Cultured Human Dermal Fibroblasts, and Decreases UVB-Induced Wrinkle Formation Following Topical Application on the Dorsal Skin of Hairless Mice.” Biological and Pharmaceutical Bulletin, vol. 30, no. 8, 2007, pp. 1395–1399, 10.1248/bpb.30.1395. Accessed 1 Oct. 2021.

[12] “Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice.” Cell Metabolism, vol. 32, no. 3, Sept. 2020, pp. 447-456.e6, www.ncbi.nlm.nih.gov/pmc/articles/PMC8508957/, 10.1016/j.cmet.2020.08.004. 

[13] “Buck Institute Study: Bodybuilding Supplement Might Boost Health.” The Mercury News, 7 Sept. 2020, www.mercurynews.com/2020/09/07/buck-institute-study-bodybuilding-supplement-might-boost-health/. Accessed 3 Jan. 2023.

[14] Matthews, R. T., et al. “Coenzyme Q10 Administration Increases Brain Mitochondrial Concentrations and Exerts Neuroprotective Effects.” Proceedings of the National Academy of Sciences, vol. 95, no. 15, 21 July 1998, pp. 8892–8897, 10.1073/pnas.95.15.8892. Accessed 25 Aug. 2021.

[15] Shults, Clifford W., et al. “A Possible Role of Coenzyme Q10in the Etiology and Treatment of Parkinson’s Disease.” BioFactors, vol. 9, no. 2-4, 1999, pp. 267–272, 10.1002/biof.5520090223. Accessed 3 Jan. 2023.

[16] “A Possible Role of Coenzyme Q10in the Etiology and Treatment of Parkinson’s Disease.” BioFactors, vol. 9, no. 2-4, 1999, pp. 267–272, 10.1002/biof.5520090223. Accessed 3 Jan. 2023.

[17] “Brain Imaging Suggests Neurotransmitter Imbalance in ALS | ALZFORUM.” Www.alzforum.org, www.alzforum.org/news/research-news/brain-imaging-suggests-neurotransmitter-imbalance-als. Accessed 3 Jan. 2023.

[18] Jia, Haiqun, et al. “High Doses of Nicotinamide Prevent Oxidative Mitochondrial Dysfunction in a Cellular Model and Improve Motor Deficit in a Drosophila Model of Parkinson’s Disease.” Journal of Neuroscience Research, vol. 86, no. 9, 1 July 2008, pp. 2083–2090, pubmed.ncbi.nlm.nih.gov/18381761/, 10.1002/jnr.21650. Accessed 3 Jan. 2023.

[19] Sun, Nuo, et al. “The Mitochondrial Basis of Aging.” Molecular Cell, vol. 61, no. 5, Mar. 2016, pp. 654–666, 10.1016/j.molcel.2016.01.028.

[20] Cui, Xu, et al. “Niacin Treatment of Stroke Increases Synaptic Plasticity and Axon Growth in Rats.” Stroke, vol. 41, no. 9, Sept. 2010, pp. 2044–2049, 10.1161/strokeaha.110.589333. Accessed 21 May 2022.

[21] Walmsley AR, Mir AK. Targeting the Nogo-A signalling pathway to promote recovery following acute CNS injury. Curr Pharm Des. 2007; 13: 2470–2484.CrossrefMedlineGoogle Scholar

[22] “Neurite Outgrowth.” QPS Neuropharmacology, qpsneuro.com/in-vitro-services/neuronal-plasticity/neurite-outgrowth/. Accessed 3 Jan. 2023. 

6 Ways to Help You Manage Your ALS Symptoms

ALS, Supplements, Uncategorized, ,

natural remedies for als

Those living with ALS experience a vast and varying degree of complications that accompany the disease. Although there have been extensive advancements with remedies, treatments, and devices, resources are limited and complex. Daily living proves difficult in even the simplest tasks. Yet, not everything must be so difficult. Here’s a list of simple and natural ways to help you with your symptoms and overall wellbeing.

  1. Eat a Nutritional Diet – The most important part of a nutritional diet for PALS is to remove toxins and eliminate the risk of damaging motor neurons by free radicals. Remove all sugars and processed foods1. Next you will need to introduce nutrient-dense and whole foods filled with antioxidants, vitamins, and minerals. Organic foods like free range chicken, grass-fed beef, healthy fats, and fruits and vegetables are examples of quality nutritional foods.
  2. Exercise – To help prevent atrophy, improve mobility, and strengthen muscles, non-exhaustive exercise has shown to be beneficial in patients with ALS. Typical exercise regiments should consist of aerobic exercise, breathing exercises, stretching, and light resistance movements. Also, for those in more advanced stages of ALS, caregiver assisted stretching is beneficial to prevent pressure point sores and contractures. Overall, exercise for ALS may slow progression of motor neuron degradation, help patients maintain a high level of function, and improve respiratory capacity3. It is advised to seek a professionally developed program designed by a licensed physical therapist.
  3. Occupational Therapy – This type of therapy provides rehabilitative care for activities required in daily living to patients recuperating from a physical or mental illness. Difficulties that occur for patients with ALS such as bathing, dressing, swallowing, and walking are fundamentally improved through programs of occupational therapy. Assisted devices, tools, and clothing, which can facilitate mobility and daily activities, are easily accessible. Studies show that people with ALS involved in multidisciplinary programs have longer life spans, due to social involvement and better mental health4.
  4. Supplements – A great way to ensure ALS patients are getting the appropriate vitamins, minerals and nutrients is through supplements for ALS. Avoiding malnutrition and ensuring an adequate dietary intake is a key factor in preventing atrophy, infection, and a weakened immune system5. Antioxidants and detoxifiers are equally important for preventing damage from oxidation and free radicals. Although there are various supplements that are recommended for patients with ALS, some of the more notable ones are Vitamin E and C, Vitamin B-complex, AAKG, GABA, Ubiquinol, Niacin, Vitamin D, CoQ10, Calcium, Magnesium, Selenium, Zinc, and fish oil1. The best supplements for ALS provide several benefits such as: energy production, detoxification, maintaining bone and muscle mass, improving cellular and mitochondrial function, and more1. You can find many of these supplements at simplesanutrition.com.
  5. Emotional Support – The burdens of ALS do not only affect the body, but places a heavy toll on mental and emotional health. The stress of coping with a debilitating disease is difficult to manage. Support from family and caregivers is essential to emotional well-being. For help with managing stress, depression or anxiety it can be very helpful to work with a therapist trained in cognitive behavioral therapy, which emphasizes the importance of underlying thoughts in determining how we feel and act6. There are also various support groups and forums where you can speak to others in similar circumstances.
  6. Sleep and Rest – One of the various struggles in managing ALS is constant exhaustion compounded by the inability to get restful sleep. The lack of sleep can cause another layer of complications to add to the already difficult effects of ALS. To prevent this restless cycle, there are some tips to help you secure better sleep. Some of these activities are: being active during the day, aromatherapy, eating foods that increase serotonin and melatonin, taking magnesium, adhering to a sleep schedule, drinking tea, taking a warm bath, exercise, meditation, reading, and taking soothing natural herbs. Other remedies for trouble sleeping due to pain include muscle rubs using lavender and peppermint oils, massage therapy and acupuncture, Epsom salt baths, and foam roller exercises, with the approval of a physical therapist. New remedies such as Hemp-Oil show promise in soothing and calming patients and getting them in a more restful mindset.

This is not an all-encompassing or complex list of suggestions for help with your ALS systems, but rather a simplified and natural way to tweak your daily routine. Make changes and introduce new habits at a rate that is comfortable for you. These tips can be implemented easily and may have significant improvements on living with ALS. Stay strong!

References:

  1. Levy, Jillian. “Lou Gehrig’s Disease (+ 6 Ways to Help Manage ALS Symptoms).” Dr. Axe Food is Medicine, 1 Feb. 2018, https://draxe.com/lou-gehrigs-disease/.
  2. Tedone M.D., V.M., Tedone-Gage, D., & Tedone, C. The Deanna Protocol Hope for ALS and Other Neurological Conditions. Tampa: Paradies/ Inspire, LLC, 2015. Print.
  3. Andrew J Lui, Nancy N Byl. A Systematic Review of the Effect of Moderate Intensity Exercise on Function and Disease Progression in Amyotrophic Lateral Sclerosis. JNPT Vol 33, June 2009 p68-87.
  4. Arbesman, Marian; Sheard, Kendra. “Systematic Review of the Effectiveness of Occupational Therapy–Related Interventions for People With Amyotrophic Lateral Sclerosis.” AJOT, Jan. 2014, https://ajot.aota.org/article.aspx?articleid=1863110/.
  5. Rosenfeld, Jeffrey, and Amy Ellis. “Nutrition and Dietary Supplements in Motor Neuron Disease.” Physical medicine and rehabilitation clinics of North America 19.3 (2008): 573–x. PMC. Web. 4 Oct. 2018.
  6. Levy, Jillian. Cognitive Behavioral Therapy Benefits & Techniques. Dr. Axe Food is Medicine, 30 Apr. 2018, https://draxe.com/cognitive-behavioral-therapy/.

Lyme Disease and ALS – Summer 2017

Blog, Uncategorized, ,

There is a lot of controversy regarding the connection between Lyme disease and ALS.

To understand the debate, let’s discuss some basics of both diseases as described by the experts.

lymediseaseimage

What is Lyme Disease:

Most people know that you get Lyme Disease from an infected tick, but many people don’t understand or realize the damage caused by Lyme Disease. If left untreated, the disease can lead to severe and life threatening medical issues.

“Lyme disease, the most common vector-borne illness in the United States, is a multi-system illness usually caused by infection with the spirochete Borrelia burgdorferi and the body’s immune response to the infection.[1] The disease is transmitted to humans via tick bites, from infected ticks of the genus Ixodes.”[1]

What is Amyotrophic Lateral Sclerosis (ALS)?

ALS is a progressive neurodegenerative disorder for which there is no cure.  Life expectancy following a diagnosis is two to five years.

“Amyotrophic lateral sclerosis (ALS), sometimes called Lou Gehrig’s disease, is a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells (neurons) that are responsible for controlling voluntary muscles (muscle action we are able to control, such as those in the arms, legs, and face). This disease belongs to a group of disorders known as motor neuron diseases, which are characterized by the gradual degeneration and death of motor neurons.”[2]

How are these two diseases different?

ALS is currently an incurable disease. Lyme disease can be treated when discovered in a timely manner by antibiotics. If left untreated, Lyme disease can result in devastating medical problems and death. Lyme disease is known to mimic many of the symptoms of other diseases causing issues on diagnosis and subsequent treatment.

Because ALS and Lyme disease can exhibit similar symptoms, incidents of misdiagnosis of Lyme Disease as ALS have been reported.  This very recent case reported by NBC highlights a misdiagnosis of ALS when the patient actually had Lyme disease. The patient’s doctor insisted he had ALS, and they accepted the reality of this diagnosis.

“Matt remembered.”He said, “Enough’s enough. The reality is, you have ALS, and you know, you really need to embrace what I am telling you.” Matt’s family was told to help him come to terms with his death.

But inside their home, the Slatner family was doing their own research on Lyme symptoms and everything kept pointing to those tick bites.

“Every single thing is a Lyme symptom,” Stephanie said, remembering the long days and nights of research, three busy kids, and a husband who was slowly fading away. “No one would listen. I mean, they made us both feel like we were crazy.”[3]

Does everyone with ALS have Lyme?

“Lyme disease does not cause ALS, and generally in a diagnostic workup, a neurologist can easily separate ALS from Lyme infections, either clinically or with testing.”[4]

Despite the current belief that Lyme disease does not cause ALS, some studies have shown that many PALS do test positively for Lyme. This has caused a lot of disagreement between physicians and patients citing high statistical evidence of Lyme in many patients with ALS as more than just a coincidence.

Lyme Disease mimics other diseases

ALSLYME

( Image Ref: http://lymediseaseguide.org/wp-content/uploads/2011/07/lyme-disease-treatment-diagnosis.gif)

Does Lyme cause ALS? 

Many ALS patients have tested positively for Lyme disease, but not all Lyme patients develop ALS.  Currently, there is no definitive proof that Lyme disease causes ALS. Although often mistaken for ALS with similar symptoms, Lyme can be treated with antibiotics and other protocols dependent on the severity and progression. A cure for ALS still has not been found, but the Deanna Protocol has been shown to help with quality of life.

This topic continues to be a source of debate among physicians and PALS, with controversy evident on the internet and social media. If you are bitten by a tick, please seek medical attention immediately.

For more information on Lyme Disease: visit http://www.cdc.gov/lyme/

For more information on ALS: http://www.alsa.org/about-als/ 

[1] Ref: http://emedicine.medscape.com/article/330178-overview

[2] Ref: http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_ALS.htm

[3] http://m.nbc12.com/nbc12/db/345738/content/i7HSWfXF/gallery

[4] https://www.washingtonpost.com/opinions/five-myths-about-als/2014/08/22/70007ef2-2842-11e4-86ca-6f03cbd15c1a_story.html

Newest Update on Deanna Protocol

Uncategorized

A recent article was released in March 2017, that examined an earlier study on the Deanna Protocol (DP).  The newest study concluded:

Targeting energy metabolism with the DP supplement as a metabolic therapy produces a change in the global metabolic profile of ALS mice that support the role of the DP for enhanced mitochondrial energy metabolism and prolongs time to paralysis of ALS C. elegans. (1)

For more information on the original article on please view the original article at:  https://link.springer.com/article/10.1007/s11306-017-1183-1

If you need information on how the Deanna Protocol can help you please contact us today for details and assistance.

Flu Season & Keeping Healthy

Blog, Resources, Uncategorized, , , , ,

The Flu season impacts a lot of people this time of year. There is always a lot of media about getting sick, so we have compiled some useful resources that could come in handy to stay healthy.

When is Flu Season?
The Flu season runs from October into late spring. The CDC says “the flu season begins when certain key flu indicators (for example, levels of influenza-like illness (ILI), hospitalization and deaths) rise and remain elevated for a number of consecutive weeks. Usually ILI increases first, followed by an increase in hospitalizations, which is then followed by increases in flu-associated deaths.” ¹

What is the difference between a Cold and the Flu?
Both a cold and Flu are respiratory illnesses. Typically, a cold is far less severe in nature and duration. Most of us know all too well that a bad cold and related symptoms will usually last for a few days or a week. Lingering symptoms that persist or worsen can indicate you have the Flu or a secondary concern.  Flu symptoms can make you ill for days to even weeks.

Why is the Flu a big deal?
No one likes to get sick, and getting a nasty cold during cold weather seems bad enough. A Flu can often be far worse in symptoms, downtime, and complications than a typical cold.
For those with chronic illness or disabilities it can be an incredibly dangerous. A recent article and video from CNN tells many “It’s time to get your flu shot.” Those who are young, old, or at risk from the complications that might occur from the Flu on a weaker immune system need to be protected.

Fight the Flu
Fight the Flu

How to protect yourself from the Flu?
One suggested precaution is to get the Flu vaccination / shot. The Flu vaccination this year is “expected to be more effective than last season.” ² It is recommended that not only should high risk people get the shot, but also those who spend time around them. Caretakers and family members also have be cautious as they can be contagious and transmit the Flu.

Why do I need a Flu shot every year?
Many wonder why we need to get another Flu vaccination every year. The reason is simple: the virus changes. A recent article in USA Today states that doctors are anticipating this to be a tough season and a nasty Flu. “Dr. Robin Altman, chief of general pediatrics for Children’s & Women’s Physicians of Westchester, suspects this may be another tough battle with the virus. Altman is urging patients to get vaccinated now, since it takes two weeks for the body to build up immunity. The flu vaccine remains the best protection against the virus.”³

I have ALS should I get the Flu Shot?
Protecting those with ALS from the Flu is very important. The ALS Association wrote a recent article about what you need to know to protect people with ALS from the Flu. Avoiding crowded places or people who are sick with either a cold or Flu is recommended. Some common sense and good hygiene are suggested. Caretakers and family members of those with ALS may want to get vaccinated.  ALS patients should always discuss the benefits and risks of getting vaccinated with their doctor. 4

A Flu for a person with weak swallowing and respiratory processes represents a significant health issue. Additional information on the Flu Virus and protecting your family and yourself this Flu season can also be found on: http://www.earlydetectionplan.org/

SOURCES

[1] http://www.cdc.gov/flu/about/season/flu-season-2015-2016.htm

[2] http://www.cnn.com/2015/10/07/health/flu-shot-vaccine-2015/

[3] http://www.usatoday.com/story/news/nation-now/2015/10/05/flu-season-underway/73383394/

[4] http://www.alsa.org/news/vision-express/articles/october-2015/flu-season.html

Lyme Disease and ALS

Blog, Uncategorized, ,

There is a lot of controversy regarding the connection between Lyme disease and ALS.

To understand the debate, let’s discuss some basics of both diseases as described by the experts.

lymediseaseimage

What is Lyme Disease:

Most people know that you get Lyme Disease from an infected tick, but many people don’t understand or realize the damage caused by Lyme Disease. If left untreated, the disease can lead to severe and life threatening medical issues.

“Lyme disease, the most common vector-borne illness in the United States, is a multi-system illness usually caused by infection with the spirochete Borrelia burgdorferi and the body’s immune response to the infection.[1] The disease is transmitted to humans via tick bites, from infected ticks of the genus Ixodes.”[1]

What is Amyotrophic Lateral Sclerosis (ALS)?

ALS is a progressive neurodegenerative disorder for which there is no cure.  Life expectancy following a diagnosis is two to five years.

“Amyotrophic lateral sclerosis (ALS), sometimes called Lou Gehrig’s disease, is a rapidly progressive, invariably fatal neurological disease that attacks the nerve cells (neurons) that are responsible for controlling voluntary muscles (muscle action we are able to control, such as those in the arms, legs, and face). This disease belongs to a group of disorders known as motor neuron diseases, which are characterized by the gradual degeneration and death of motor neurons.”[2]

How are these two diseases different?

ALS is currently an incurable disease. Lyme disease can be treated when discovered in a timely manner by antibiotics. If left untreated, Lyme disease can result in devastating medical problems and death. Lyme disease is known to mimic many of the symptoms of other diseases causing issues on diagnosis and subsequent treatment.

Because ALS and Lyme disease can exhibit similar symptoms, incidents of misdiagnosis of Lyme Disease as ALS have been reported.  This very recent case reported by NBC highlights a misdiagnosis of ALS when the patient actually had Lyme disease. The patient’s doctor insisted he had ALS, and they accepted the reality of this diagnosis.

“Matt remembered.”He said, “Enough’s enough. The reality is, you have ALS, and you know, you really need to embrace what I am telling you.” Matt’s family was told to help him come to terms with his death.

But inside their home, the Slatner family was doing their own research on Lyme symptoms and everything kept pointing to those tick bites.

“Every single thing is a Lyme symptom,” Stephanie said, remembering the long days and nights of research, three busy kids, and a husband who was slowly fading away. “No one would listen. I mean, they made us both feel like we were crazy.”[3]

Does everyone with ALS have Lyme?

“Lyme disease does not cause ALS, and generally in a diagnostic workup, a neurologist can easily separate ALS from Lyme infections, either clinically or with testing.”[4]

Despite the current belief that Lyme disease does not cause ALS, some studies have shown that many PALS do test positively for Lyme. This has caused a lot of disagreement between physicians and patients citing high statistical evidence of Lyme in many patients with ALS as more than just a coincidence.

Lyme Disease mimics other diseases

ALSLYME

( Image Ref: http://lymediseaseguide.org/wp-content/uploads/2011/07/lyme-disease-treatment-diagnosis.gif)

Does Lyme cause ALS? 

Many ALS patients have tested positively for Lyme disease, but not all Lyme patients develop ALS.  Currently, there is no definitive proof that Lyme disease causes ALS. Although often mistaken for ALS with similar symptoms, Lyme can be treated with antibiotics and other protocols dependent on the severity and progression. A cure for ALS still has not been found, but the Deanna Protocol has been shown to help with quality of life.

This topic continues to be a source of debate among physicians and PALS, with controversy evident on the internet and social media. If you are bitten by a tick, please seek medical attention immediately.

For more information on Lyme Disease: visit http://www.cdc.gov/lyme/

For more information on ALS: http://www.alsa.org/about-als/ 

[1] Ref: http://emedicine.medscape.com/article/330178-overview

[2] Ref: http://www.ninds.nih.gov/disorders/amyotrophiclateralsclerosis/detail_ALS.htm

[3] http://m.nbc12.com/nbc12/db/345738/content/i7HSWfXF/gallery

[4] https://www.washingtonpost.com/opinions/five-myths-about-als/2014/08/22/70007ef2-2842-11e4-86ca-6f03cbd15c1a_story.html

Finding Financial Assistance for ALS Patients

Blog, Resources, Uncategorized, ,

A diagnosis of ALS is devastating news for patients and their family. Dealing with the extensive costs associated with any chronic illness only adds additional burden and stress. Some care is covered by a patient’s health insurance but some costs are not considered customary or reasonable, or not approved by some carriers. In a recent study called the economic impact of amyotrophic lateral sclerosis: a systematic review by Matthew Gladman, and Lorne Zinman found that “costs associated with ALS were greater than other neurological diseases.”[1] Another abstract indicated that there are few published reports on the cost of ALS care in the United States, but wanted to so examine those costs and identified strategies to assist patients with these expenses. The study: Financial cost of amyotrophic lateral sclerosis: A case study March 2015 concluded that: Continue reading Finding Financial Assistance for ALS Patients →

Preparing for Emergencies When You Have ALS

Blog, Deanna Protocol, Resources, Uncategorized,

Emergencies can be frightening and dangerous for anyone. When you have a chronic illness like ALS, natural disasters pose additional risks for those who have limited mobility or are homebound.

Recently, the ALS Association posted a wonderful Emergency Preparedness Checklist for People with ALS. One of the most important things to do is to be proactive in case of emergency. The ALS breaks it down for you suggesting to take the time and work to prepare as you will then feel less vulnerable if and when an emergency arises. These disasters could include natural disasters, home fires, acts of terrorism, or accidental occurrences.
Continue reading Preparing for Emergencies When You Have ALS →

Deanna Protocol Multi-Pack Overview

Blog, Deanna Protocol, Uncategorized

Simplesa offers convenient Deanna Protocol Multi-Packs with our DPS-AM & DPS-PM Blends. The Multi-Packs are a convenient option for ensuring you have everything you need for a 30-day supply. Each Multi-Pack offers the same nutrients, with a liquid and powder focus. Below is an explanation of each Multi-Pack.multi-pack-w-akg-liquid-ampm-powders.jpg
Continue reading Deanna Protocol Multi-Pack Overview →

Simplesa – A Simplified Approach

Blog, Deanna Protocol, Uncategorized,

At Simplesa, we make complex nutrition simple. We are consistently looking for ways to formulate products that combine well researched and document nutrients, which target a specific health focus and blend them together for an all-inclusive approach that not only saves our customers money, it also provides optimal nutritional support.
Continue reading Simplesa – A Simplified Approach →