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20 things to know regarding Pharmaceutical vs. Nutraceutical protocols for ALS!

Radicava® vs Deanna Protocol®

To understand what the differences between Pharmaceutical and Nutraceutical are, we should begin with their definitions:



  1. Relating to medicinal drugs, or their preparation, use, or sale.


  1. a compound manufactured for use as a medicinal drug.



Plural noun: nutraceuticals 

a food containing health-giving additives and having medicinal benefit.

Now, let’s compare the new drug approved by the FDA Radicava® vs The Natural alternative for a better quality of life, the Deanna Protocol®.

  • 10 Things to Know About the New ALS Drug Radicava®
  1. It is a Pharmaceutical drug.
  2. The drug underwent a phase 3 clinical trial in Japan and South Korea where 137 ALS patients were given either Radicava® or a placebo. The group given Radicava® experienced a 33 percent reduction in the decline of their physical abilities compared to the placebo group.
  3. Radicava® works by reducing the oxidative stress in the body. People with ALS have high levels of oxidative stress.
  4. Radicava® is administered via intravenous infusions. Initially, patients have a daily infusion for two weeks and then have two weeks’ rest. After that, they need to have 10 consecutive daily infusions followed by two weeks of rest.
  5. Each infusion takes around an hour to complete.
  6. The dosage of each infusion is 60 mg.
  7. The cost of each Radicava® infusion is about $1,000 and it’s reported that the treatment costs about $146,000 annually.
  8. Radicava® should be available to ALS patients in the U.S. by August.
  9. The most common side effects associated with the drug are headaches, bruising and gait problems.
  10. Radicava® infusion contains sodium bisulfite which is known to cause both mild and severe allergic reactions in some people (particularly those with asthma).
  • 10 Things to Know About the Deanna Protocol®
  1. It is a naturally derived Nutraceutical program.
  2. Developed by Doctor Vincent Tedone, a retired physician (Orthopedic Surgeon), for his daughter Deanna who was diagnosed with ALS at the age of 30 in 2007.
  3. The Deanna Protocol® has undergone double blind clinical trials at the University of South Florida in mice models. The Deanna Protocol® has over 1,500 anecdotal case studies from patients with ALS.
  4. The Deanna Protocol® is a blend of nutritional powders and liquids that contain powerful antioxidants and amino acids essential to assist your body in its natural efforts to fight neurodegenerative damage. People suffering from other neurodegenerative diseases, such as Parkinson’s and Alzheimer’s, have also reported improvements.
  5. It is taken in the morning, in the afternoon and at night as part of your regular, at home, breakfast, lunch and dinner routine. No need to go to the clinic.
  6. The Protocol is the same for everyone but the dosages might vary, depending on the person and what their specific needs are. The most common side effect is an upset stomach usually reported during the initial days as the body adjusts to the protocol.
  7. The cost of the Deanna Protocol® starts at $219.99 for the Core Bundle #1. The next most inclusive package is the Plus Bundle #1 at $249.99. And our most inclusive bundle is the Comprehensive Bundle #1 at $349.99. Above prices are for a 1 month supply and include easy-to-follow, step-by-step instructions and an actual human to answer your questions and provide you with the support you need.
  8. Not sure? At Simplesa’s website there’re 330+ reviews with 4.5 stars from verified and satisfied buyers at simplesanutrition.com or call 1-888-578-5528.
  9. Deanna Protocol® has been in the market for almost 4 years. The popularity of the protocol and the positive reports from the clients, speak for themselves.
  10. The freshness of the products used in the Deanna Protocol is guaranteed, these products are naturally derived and are manufactured in a facility that follows strict Current Good Manufacturing Practice (cGMP) (Enforced by the FDA) and is UL (Underwriters Laboratories) certified.

 This Blog is for educational purposes. We hope that the above information helps you make the right decisions to address your neuro-degenerative concerns. And as always consult your physician.

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These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any diseases.



The Deanna Protocol® Continues to Impress ALS Patients

The Deanna Protocol is an all-natural metabolic program developed by Dr. Vincent Tedone which is continuing to improve the quality of life for people with ALS.

It was just a few years ago that the Ice Bucket Challenge caught everyone’s eye and raised awareness for ALS, or Lou Gehrig ’s disease.  At the time the Deanna Protocol® was relatively new but it was already helping many ALS patient’s lives.  According to a study by Winning the Fight, which researches “The Deanna Protocol,” a metabolic therapy with Deanna Protocol supplementation delays disease progression and extends survival in an amyotrophic lateral sclerosis (ALS) mouse model.[1] The benefits of the Deanna Protocol to patients with ALS (PALS) is evident in the anecdotal feedback in recent years.

The Deanna Protocol® Metabolic Plan (also known as the DP™Plan) is a natural, drug-free, and inexpensive metabolic program developed for ALS. Scientific studies have proven that the DP™ Plan significantly slows the progression of ALS and extends life span. The DP™Plan is not an ALS treatment drug like Rilutek/Riluzole. It is a list of substances (AAKG, AKG, GABA, CoQ10, Niacin, and 5HTP) that are already found in the body. However, the amounts found in the body are not nearly enough for those who have ALS, so the DP™Plan provides the body and nerve cells with more of these substances to compensate for what they lack.  It is determined that the substances in the DP™ Plan provide energy to cells that are dying and in doing so keeps them alive.  This is very important because when nerve cells die, they release glutamate which kills the contiguous cells.[2]

In 2014 CBN News wrote that ‘Deanna Protocol’ Makes a Splash in ALS Research’. The study found “mice on The Deanna Protocol had improved neurological scores, increased motor function and most importantly, survived longer than the mice who weren’t on it.”[3]  Since this initial article, the Deanna Protocol has evolved in several major ways, in conjunction with assistance from Simplesa’s commitment to the ALS Community.  Simplesa® was founded in 2013 because it saw a need and had a solution.  ALS patients were having success following the Deanna Protocol, but it was too complex and expensive the way it was distributed. Simplesa® formulated products specifically for these ALS patients to simplify their regimen and lower the cost of the metabolic protocol.

Now all of the products needed to follow the protocol are offered in easy to follow combinations. Due to the improved ease of following the Deanna Protocol with the Simplesa products, the number of people following the protocol has increased. As the number of PALS following the Deanna Protocol has increased, Simplesa has also been able to reduce the cost of the protocol.  Additionally, to add further savings and flexibility to PALS, Simplesa® and Winning the Fight® teamed up to break the Deanna Protocol down into three bundled and more personalized options: Deanna Protocol Core, Plus, and Comprehensive Bundles.

The Deanna Protocol Core Bundle focuses on six essential nutrients of the Deanna Protocol. These nutrients primary support providing energy production to the body through the mitochondria of the cells.  The Plus Bundle builds on the Core Bundle by adding in Liposomal Glutathione, which helps the body push out toxins. It is considered the best antioxidant for the nervous system.  The Comprehensive Bundle builds on the Plus Bundle by adding in the AM & PM Blends. These blends come in two powders, one for the morning and one for the evening, and they contain an additional 20 amino acids that support muscle and nerve health. These combinations are based on the research publication by the NIH on nutrients that should be consumed by people who have ALS.

The affirmative feedback and reports from PALS to Simplesa® on the Deanna Protocol® have been very positive in the years since its inception.  PALS have continued to report improvement in quality of life:

“This product has worked wonders helping to reduce my pain, improve energy, lessen the severity muscle spasms, as well as improve balance and vertigo. I notice a day and night difference within taking my morning dose. I recommend taking the AKG throughout the day, not in lump 3 times a day to improve energy life.”

“My husband has been on the Deanna Protocol Products for two months now. He feels he has more energy and strength. We Would recommend these products!”

For more personal accounts on how the Deanna Protocol is helping PALS please click here.

The Deanna Protocol is not a cure for ALS, but it is a natural metabolic protocol that can help PALS improve their quality of life. To find out more about the Deanna Protocol® please contact Simplesa’s support team for information to see how it can help you or someone you know impacted by ALS.



[1] https://www.ncbi.nlm.nih.gov/pubmed/25061944
[2] https://www.winningthefight.org/deanna-protocolreg-metabolic-plan-for-als.html
[3] http://www1.cbn.com/cbnnews/healthscience/2014/August/Deanna-Protocol-Gains-Ground-in-ALS-Research

The Fight against Neurodegenerative Diseases

The recent death of Muhammad Ali has saddened a lot of people and reinforced the urgent need to aggressively develop a cure for neurodegenerative diseases.  ALS, Parkinson’s, Alzheimer’s, and other neurodegenerative diseases have very similar characteristics regarding their causes and symptoms. They also all have no cure and are impacting too many people.

Parkinson’s disease (PD) and amyotrophic lateral sclerosis (ALS) are the second and third most common human adult-onset neurodegenerative diseases, respectively, after Alzheimer’s disease. They are characterized by prominent age-related neurodegeneration in selectively vulnerable neural systems. Some forms of PD and ALS are inherited, and genes causing these diseases have been identified. Morphological, biochemical, and genetic, as well as cell and animal model studies reveal that mitochondria could have a role in this neurodegeneration. The functions and properties of mitochondria might render subsets of selectively vulnerable neurons intrinsically susceptible to cellular aging and stress and overlying genetic variations. In PD, mutations in putative mitochondrial proteins have been identified and mitochondrial DNA mutations have been found in neurons in the substantia nigra. In ALS, changes occur in mitochondrial respiratory chain enzymes and mitochondrial cell death proteins.[1]

Beyond the genetic factors to inherit these diseases, many who have had traumatic brain injury are at an increased risk of developing one of these debilitating diseases. Athletes who are involved in boxing, football and hockey, Veterans, and others are especially susceptible:

Over a lifetime, we believe that Parkinson’s and several other neurodegenerative diseases are caused by genetics AND some kind of trigger in a person’s life with age. For example, inflammation in brain tissue caused by either genetic susceptibility or triggered by accumulating cellular proteins and external events, such as severe concussions, will leave the brain more open to injury. [2]

Amyotrophic Lateral Sclerosis (ALS)

ALS attacks the nerve cells located in the brain and spinal cord (motor neurons). As the disease progresses, the patient loses the ability to control muscle movement as the motor neurons die. ALS is a terminal disease currently with no cure. Metabolic treatments like the Deanna Protocol have been reported by patients to improve quality of life for those with ALS. The ALS.org shared this amazing infographic to help increase awareness and knowledge about ALS – See:  http://web.alsa.org/site/PageNavigator/Chal15_what_is_ALS.html?_ga=1.11083444.1475505218.1462481428

Parkinson’s Disease

This is a progressive and neurodegenerative disease whose cause and cure is currently unknown. Nerve cells in the brain malfunction and die.

Motor symptoms result from the loss of pigmented neurons or cells in the substantia nigra of the brain. These cells produce dopamine, a chemical responsible for smooth purposeful movement. A decrease in dopamine does not account for all symptoms experienced in PD. Research is ongoing to better understand the pathology of Parkinson’s. [3]

Alzheimer’s Disease

Despite a common misconception, Alzheimer’s is not a normal part of aging. The damage and death of nerve cells causes the symptoms most commonly associated with this disease:

  • Loss of Memory
  • Inability to carry out normal or daily activities
  • Personality changes

The brain has 100 billion nerve cells (neurons). Each nerve cell connects with many others to form communication networks. Groups of nerve cells have special jobs. Some are involved in thinking, learning and remembering. Others help us see, hear and smell.

To do their work, brain cells operate like tiny factories. They receive supplies, generate energy, construct equipment and get rid of waste. Cells also process and store information and communicate with other cells. Keeping everything running requires coordination as well as large amounts of fuel and oxygen.

Scientists believe Alzheimer’s disease prevents parts of a cell’s factory from running well. They are not sure where the trouble starts. But just like a real factory, backups and breakdowns in one system cause problems in other areas. As damage spreads, cells lose their ability to do their jobs and, eventually die, causing irreversible changes in the brain.[4]

A recent study by researchers from Indiana University, concludes that:

An enzyme that protects the brain against oxidative stress may also protect against the formation of protein clumps – a hallmark of Alzheimer’s, Parkinson’s, and other neurodegenerative diseases. An accumulation of protein clumps is known to occur in a number of neurodegenerative diseases, including Alzheimer’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS) – also known as Lou Gehrig’s disease. In Alzheimer’s disease, for example, studies have shown that patients often experience a build-up of a protein called tau, which clumps together in nerve cells to form “tangles.” This process – known as proteinopathy – occurs with different proteins in a variety of brain diseases and is believed to play a role in their progression.[5]

Every day someone we know or love is struggling with the challenges of a neurodegenerative disease, and many are dying. It is important to understand how these diseases are connected so we can find a cure for them all.

The Deanna Protocol® Metabolic Plan for Other Neurodegenerative Conditions

Winning the Fight ® (WFND) plans to begin researching the DP™ Plan and its effectiveness in conditions other than ALS. Why? Other neurodegenerative conditions (such as stroke, traumatic brain injury, concussion, Alzheimer ’s Disease, Parkinson’s Disease, Multiple Sclerosis, and more) may have different causes, but they all share one common denominator: Glutamate. Regardless of the disease/condition, all nerve cells release excess glutamate into the extracellular space when they die and this glutamate will kill neighboring cells. Therefore, nerve cell death probably spreads throughout the nervous system the same way in all of these conditions. Since the DP™ Plan manages the spread of neuron death, it could likely help manage all neurodegenerative conditions, regardless of their initial cause.

WFND has one case study showing that the DP™ Plan is extremely effective in dramatically reversing the effects of Alzheimer’s Disease, even in the advanced stages of the disease. This further encourages us to test Dr. Tedone’s hypothesis that the DP™ Plan may manage many conditions aside from ALS. They plan to conduct research testing the DP™ Plan’s effectiveness in the neurodegenerative conditions mentioned above. They also plan to test the effectiveness of the combination of the DP™ Plan and GOT in each of the aforementioned conditions above. Lastly, they aim to customize the DP™ Plan and the DP™ Plan/ GOT combination for each distinct disease.[6]

​For more information on the DP™ visit:  https://www.simplesanutrition.com/deanna-protocol/

[1] http://www.ncbi.nlm.nih.gov/pubmed/20413846

[2] http://www.mcleanhospital.org/news/2016/06/05/fighting-parkinsons-lab

[3] http://www.apdaparkinson.org/parkinsons-disease/understanding-the-basics/

[4] http://www.alz.org/alzheimers_disease_what_is_alzheimers.asp#brain

[5] http://sourceinformer.com/index.php/2016/06/05/neurology-neuroscience-alzheimers-dementia-parkinsons-disease-muscular-dystrophy-als-brain-enzyme-could-prevent-alzheimers-neurodegenerative-disease/

[6] http://www.winningthefight.org/why-the-deanna-protocolreg-plan-works.html

Nutritional Challenges for PALS

May is ALS Awareness month, and during this time of raising awareness it is also important to discuss some things that can help PALS with maintaining their quality of life. Nutritional concerns are an issue for anyone facing any disabling disease. Every type of illness impacts people differently and maintenance of nutritional and key vitamin balance is critical for well-being.  The ALS Association wrote an article called “Maintaining Adequate Nutrition: A Continuing Challenge in ALS,” which provides some helpful information on the challenges of getting and maintaining appropriate nutrition and the impact on quality of life for PALS.  Getting adequate nutrition can be hard for even a healthy individual, but for someone with a disabling disease like ALS, who will face the additional issues of difficulty or loss of the ability to swallow, it is life threatening.

Supplements are often recommended by medical providers to help ALS/MND patients get the appropriate nutrition they need. This means getting adequate calories, vitamins and minerals. This is in addition to the ingredients in the Deanna Protocol (DP™ Plan), which have been shown in studies, and reported by many PALS, to improve quality of life.

The DP™ Plan is a natural, drug-free, and inexpensive metabolic program developed for ALS. Scientific studies have proven that the DP™ Plan significantly slows the progression of ALS and extends life span.[1]  The goal of the DP™ Plan is to provide energy to the nerve and muscle cells to prevent them from dying. To do this, the DP™ Plan includes a list of several supplements that are taken in doses throughout the day.   These supplements may be found online by doing an internet search for each supplement individually, or Simplesa® makes products in powder or liquid form and combines several of the supplements into single products. The Winning the Fight website provides very detailed information on how the DP Plan is helping not only ALS patients but is also now being tested and used on others with Neurodegenerative diseases.  Some of the key points in regard to metabolic and nutritional importance of the DP Plan are explained by Winning the Fight®:

Glutamate, ALS, and Cell Death
To understand the basis for the Deanna Protocol® Metabolic Plan, one must first consider the pathology in neurodegenerative conditions in general and ALS specifically. Death of motor neurons spreads throughout the body in individuals with ALS due to glutamate. When cells die, they burst and release intracellular glutamate into the extracellular space. This increase in extracellular glutamate causes neighboring healthy motor neurons to die, to burst, and to release more glutamate into extracellular space, which will kill even more neighboring cells. This so-called storm of glutamate in ALS causes cell death to happen at an exponential rate. (The spread of cell death via excess extracellular glutamate has already been proven in other neurodegenerative conditions, such as traumatic brain injury. It has not yet been proven in ALS research. However, we know that all cells release glutamate when they die and that excess extracellular glutamate kills neighboring cells, regardless of the disease/condition.)

​Dr. Tedone, Winning the Fight’s Medical Liaison, hypothesizes that somehow, the exposure to excess extracellular glutamate in ALS kills neighboring healthy neurons by interrupting the Krebs Cycle in each of them. Dr. Tedone’s hypothesis holds that this Krebs Cycle interruption is a chief cause of cell death. After all, when cells cannot produce energy efficiently, they die.

How the Deanna Protocol® Metabolic Plan Stops Cell Death Caused by Extracellular Glutamate in ALS 
Does the Deanna Protocol® Metabolic Plan (DP™ Plan) neutralize the excess extracellular glutamate in ALS? No. the DP™ Plan focuses on cell metabolism. The DP™ Plan delivers Alpha-ketoglutarate (AKG) to the Krebs Cycle in the neurons. The increase in AKG enables their mitochondria to produce enough energy to keep cells alive, despite their exposure to an unhealthy amount of extracellular glutamate.  AKG usually does not pass through the cell membranes in normal healthy cells.  Based on our experience, we found that the permeability of the cell membrane in diseased or damaged cells changes and allows AKG to permeate the cells. Due to the fact that AKG only enters diseased cells, the substance only goes where it is needed. [2]

The needs of anyone who has a disabling disease when it comes to nutrition is complex and varies from individual and disease. One common factor is the importance to maintain weight, nutritional balance, and allow the person enough energy to fight the disease and also maintain quality of life. For more information on the Deanna Protocol, please feel free to contact is for additional information.

[1] http://www.winningthefight.org/deanna-protocolreg-metabolic-plan-for-als.html

[2] http://www.winningthefight.org/why-the-deanna-protocolreg-plan-works.html

PALS and Nutrition

Guest Post by Sarah Martin

SarahMartinMy name is Sarah Martin. I am a junior neuroscience major at Drake University in Des Moines, Iowa. When I was 14 years old and a sophomore at the Illinois Mathematics
and Science Academy, my principal and close friend, Dr. Eric McLaren, was diagnosed with amyotrophic lateral sclerosis (ALS). ALS is a fatal neurodegenerative disease that
affects nerve cells in the brain and spinal cord. Since his diagnosis, I have been
passionate about fighting ALS. I conduct research at universities in the Midwest, attend support groups in the Chicagoland area to meet pALS and their families, blog about my journey to a cure for the disease, speak at schools about ALS and so much more! Dr.
McLaren passed away from ALS in June of 2014, but I have made it my life’s mission to
put an end to this disease. My future plans include earning a doctorate degree,
becoming an ALS researcher, and helping develop an effective treatment for ALS.
The most important part of my ALS work is the people with ALS (pALS). During my time
at ALS support groups, I have learned that because the disease is characterized by
muscle weakness and atrophy, there are a handful of challenges pALS may face in
regards to eating. Difficulties with upper body coordination may make it difficult to
prepare meals. Weakness of tongue and facial muscles may not only make it tough to
safely chew and swallow food, but can also prolong mealtimes. In addition, aspiration of
solids or liquids into the lungs can result in aspiration pneumonia. pALS may experience
a loss of appetite and fatigue which can make eating a difficult task. As ALS progresses
in a person, the amount of calories consumed typically decreases.
Proper nutrition is vital. The human body requires various nutrients to function. Due to
decreased food intake in ALS, it can be difficult to maintain nutritional needs, but there
are nutritionists, dietitians and other experts working to improve the nutritional status of
pALS. In order to maintain the nutritional needs of pALS, tips for safer chewing and
swallowing techniques can be utilized, such as taking smaller bites, eating slowly and
sitting in an upright position while eating. Healthcare professionals can also assist in
making decisions regarding alternate feeding options, such as a feeding tube.
Maintaining the nutritional needs of pALS is important as it can help slow down the
muscle breakdown process and prevent a decrease in weight loss (nutrition-related). It
can also help keep the immune system strong and improve the quality of life for those
with ALS!

For More Information about Sarah Martin contact:

Sarah’s Mission
A woman on a mission to end ALS/MND/Lou Gehrig’s disease
Follow my journey at www.sarahmartinals.com

Deanna Protocol – Nutritional/Metabolic Protocol for People with ALS

The Deanna Protocol: Help with ALS

A diagnosis of amyotrophic lateral sclerosis (ALS) may leave you feeling overwhelmed, scared, angry, depressed and confused. But there is hope and help with the Deanna Protocol®.


ALS is a progressive neurodegenerative disorder for which there is no cure. In ALS, nerve cells that control your muscles degenerate and die, leading to loss of function, including the ability to move, eat, speak and breathe. Life expectancy following a diagnosis is two to five years.

The Center for Disease Control and Prevention (CDC) estimates that ALS affects about 1.6 people per 100,000 population in the United States and that about 5,000 people are diagnosed with ALS each year. Researchers have found that in patients with ALS:

  • Nerve cells lose energy
  • Without energy the nerve cells die
  • Glutamate, a neurotransmitter (a chemical that sends messages from nerve cells to muscle cells) byproduct of cell metabolism, is present in excessive amounts

These findings led to the development of the Deanna Protocol.

The Deanna Protocol

In 2009, Dr. Vincent Tedone, a retired orthopedic surgeon, was motivated to research alternative ALS therapies when his 30-year-old daughter, Deanna, was diagnosed with the disease. He wondered if ALS could be treated similarly to diabetes, a disease in which the insulin-producing cells of the pancreas produce little or no insulin, causing high glucose levels in the blood that can damage the heart, kidneys and other organs and systems. Diabetes treatment consists of replacing the missing insulin. Dr. Tedone theorized that replacing the missing metabolic enzymes that provide cells with energy would slow ALS progression.

As a result, Dr. Tedone put together the Deanna Protocol, a metabolic therapy, that has been shown to improve muscle function, reduce symptoms and increase longevity in mice with ALS. Although no human clinical trials have been conducted at this time, patient testimonials about reduced symptoms, improved functioning and better quality of life support these findings.

The Deanna Protocol consists of:

  1. Daily intake of naturally occurring metabolic supplements to supply energy to the cells and antioxidants
  2. Massage with extra virgin coconut oil
  3. Nonexhaustive exercise, including resistance training and aerobics

For more information about the Deanna Protocol, visit Winning the Fight or Simplesa®, a nutritional supplement company.


Simplesa® is a nutritional supplement company that has developed formulations based on the Deanna Protocol. Simplesa products are the first-ever specific vitamins and supplements for ALS patients, making it easy and affordable to follow the Deanna Protocol. For more information, visit Simplesa.

Additional Support and Resources

Additional help is available from the ALS Association. This national nonprofit organization is dedicated to researching a cure for ALS and providing resources and assistance to ALS patients and their families. Visit their website to find educational materials for both patients and caregivers and for access to local programs and services that can help you cope with ALS.

Deanna Protocol Bundles – New Year, New Options, Lower Pricing

Deanna Protocol
Deanna Protocol Comprehensive Bundle


Each New Year provides new opportunities to grow and help expand our efforts to our customers.  The last year saw heightened attention and popularity of the Deanna Protocol.

A Recap of the Deanna Protocol®

The Deanna Protocol® is an all-natural metabolic program developed by Dr. Vincent Tedone through his extensive research on Amyotrophic Lateral Sclerosis (ALS or Lou Gehrig’s Disease). Scientific studies conducted on the Deanna Protocol® by Winning the Fight have shown that it benefits individuals with ALS.

Simplesa offers several choices for the Deanna Protocol®

Simplesa® understands your struggle with ALS as well as the expense and financial burden for many who want to follow the protocol. The popularity of the Deanna Protocol has enabled us to lower our costs and pass those savings on to you. We’ve reduced the price of the Deanna Protocol Bundle Packs.  The additional bundle choices include preferences for powders, capsules or liquids in the bundles.  Our goal is to make following the Deanna Protocol as simple and cost effective as possible for you!

The one thing that has not changed is that you will still get the same quality products and service you’ve always received from Simplesa!

What are the changes in the bundles for following the Deanna Protocol?

Simplesa has created new bundle packs for those choosing not to follow the full Deanna Protocol Comprehensive Approach, but instead follow core approaches.

We now offer a more varied and flexible approach with more choices for you:

1.     “CORE” Bundles contain the DP Plan Essentials;

2.     “Plus” Bundles which add Liposomal Glutathione to the Core Bundles;

3.     “Comprehensive” Bundles for an all-inclusive approach.

What are the differences between the three options?

1.     The “CORE” Bundles contain all of the DP™ Plan Essentials nutrients: AAKG, AKG, Ubiquinol, GABA, Niacin and 5-HTP. 

a.     You will see two options for the CORE Bundles

i.     “CORE” Bundle 1 – includes AKG+ Capsules

ii.     “CORE” Bundle 2 – includes AKG Liquids

1.     The difference between the two “CORE” Bundles are the choice of AKG+ Capsules or AKG Liquids

2.      The “PLUS” Bundles contain all of the DP™ Plan Essentials nutrients plus Liposomal Glutathione, considered the best antioxidant for the central nervous system.

a.     You will see two options for the “PLUS” Bundles

i.     You get the “Core” Bundle 1 plus you get Liposomal Glutathione

ii.     You get the “CORE” Bundle 2 plus you get Liposomal Glutathione


3.     The “COMPREHENSIVE” Bundles contain all of the DP™ Plan Essentials nutrients plus Liposomal Glutathione and the AM & PM Blends. Liposomal Glutathione is considered the best antioxidant for the central nervous system. The AM & PM Blends contain 20 nutrients that support muscle and nerve health based on research from the NIH.  All are included in the Winning the Fight Program for ALS.

a.     The “COMPREHENSIVE” BUNDLES give you 4 choices

i.     “COMPREHENSIVE” Bundle 1  or Bundle 2 include a choice of “CORE” 1 or 2 Bundle plus Liposomal Glutathione and AM & PM Powder Blends

1.     The difference is the choice of AKG+ Capsules or AKG Liquids combined with the AM & PM Powder Blends

ii.     “COMPREHENSIVE” Bundle 3  or Bundle 4 include the  “CORE” 1 or 2 Bundle plus Liposomal Glutathione and AM & PM Liquid Blends

1.     The difference is the choice of AKG+ Capsules or AKG Liquids combined with the AM & PM Liquid Blends


How will these changes in Simplesa® Bundles help me?

You now have more choices on how you can follow the Deanna Protocol and at lower prices.

Please click here to explore the new choices and savings on Simplesa® Deanna Protocol Bundles. If you have questions or need help please contact – we are here to help.

Simplesa Deanna Protocol

At this time there is no cure for Amyotrophic Lateral Sclerosis (ALS). Many patients facing this diagnosis are in a state of helplessness and hopelessness.

Dr. Vincent Tedone, a retired physician faced this same news when his daughter Deanna (at age 30) was initially diagnosed with ALS. Not wanting to give up and determined to find something to help her, he developed the Deanna Protocol. This all-natural metabolic therapy is a specific combination of nutrients found naturally occurring in our bodies that are administered in a consistent and daily protocol. Although not a cure for ALS, the Deanna Protocol has been reported by patients to slow the disease’s progression and allowing some individuals to achieve a better quality of life. In fact, a study performed by the University of Florida showed positive correlation and supporting results of how the Deanna Protocol supplementation delayed ALS disease progression and extended survival in mice. The study’s findings indicated that “metabolic therapy produces a therapeutic effect in ALS mice which may prolong survival and quality of life in ALS patients. “1

CaptureThe goal of the protocol is to provide supplemental energy to the nerve and muscle cells to help in the prevention of cell death. Simplesa provides pre-packaged versions of the supplements required for the Deanna Protocol. The Simplesa products offer the convenience, cost effectiveness, and consistency of quality that supports the requirements of the Deanna Protocol.
The bottom line is that battling ALS requires fighting hard until a cure is found. The Deanna Protocol offers a natural therapy that has helped many people improve their quality of life. Find out more about how it might help you or someone you know battling ALS.

For more information on the history of the Deanna Protocol please visit: http://winningthefight.org/t/Deanna-Protocol


References:  [1] http://www.ncbi.nlm.nih.gov/pubmed/25061944

Deanna Protocol Multi-Pack Overview

Simplesa offers convenient Deanna Protocol Multi-Packs with our DPS-AM & DPS-PM Blends. The Multi-Packs are a convenient option for ensuring you have everything you need for a 30-day supply. Each Multi-Pack offers the same nutrients, with a liquid and powder focus. Below is an explanation of each Multi-Pack.multi-pack-w-akg-liquid-ampm-powders.jpg
Continue reading Deanna Protocol Multi-Pack Overview

Simplesa – A Simplified Approach

At Simplesa, we make complex nutrition simple. We are consistently looking for ways to formulate products that combine well researched and document nutrients, which target a specific health focus and blend them together for an all-inclusive approach that not only saves our customers money, it also provides optimal nutritional support.
Continue reading Simplesa – A Simplified Approach