Tag Archives: supplements for ALS

Energy Expenditure in Nerve Cells continues to be a Trigger for ALS

blue neurons als treatment

Finding a cure for ALS continues to be a difficult and elusive endeavor. This is understandable since the body is a complex system. Moreover, the degree of difficulty of finding a cure goes up exponentially, when one talks about the body’s nervous system. Nevertheless, advances and findings are coming to light rather quickly and we may be one piece of the puzzle away from a major breakthrough.

One cannot help but notice that within these new findings, certain similar themes that trigger ALS keep coming up. One such theme is the damage caused by the increase in energy expenditure by the nerve cells. A recent study called “Consideration of gravity as a possible etiological factor in Amyotrophic Lateral Sclerosis” that appeared in the journal Medical Hypotheses, suggests that nerve fibers that are disposed vertically (essentially oriented vertically) can accumulate too much cell waste. This cell waste accumulation can lead to damage to the nerve cell and even to cell death. The findings suggest that the uneven distribution of nerve cell loss in PALS, can have something to do with the fact that vertically oriented nerve cell bodies (axons) consume about 2% more energy than transverse running axons.

This may not seem like much but over a period of months and years this 2% excessive energy consumption, due to gravity, may cause the accumulation of waste in vertically running axons. This can deteriorate and weaken nerve cells and can lead to the onset of ALS. Other factors such as using your right hand more frequently (if you’re right handed), or excessive exercising, or your diet, or even your emotional wellbeing can all affect the progress of ALS.

Ok, so how do I counter the effects of excessive energy expenditure? I can’t stop my nerve cells from using energy! There’re a few strategies that we can recommend:

  1.  Avoid repetitive movements and try to change your body’s orientation throughout the day. There’s a recurring link between the deterioration of the nerve cells we use most and ALS. Making small adjustments throughout the day may help reduce the energy expenditure of the same nerve cells.
  2. Increase your intake of supplements that help your nerve cells produce energy. We recommend that you look at Simplesa AAKG+ or learn more about the Deanna Protocol.
  3. Increase the intake of supplements for ALS that help eliminate cell waste (such as excess Glutamate) and that help reduce oxidative damage. Try Oxaloacetate from Natural Dynamix Endure DX. Also try Liposomal Glutathione one of the most powerful anti-oxidants available.
  4. Engage in Moderate intensity exercise that is non-exhaustive and specifically designed for patients with ALS. Learn more here Exercise Program for ALS,
  5.  Do what you can to reduce stress and stay in reasonably good emotional balance. There are many natural remedies for ALS. Reduce coffee intake, practice Yoga and meditation, and develop a deeper spiritual life. You can also try natural Hemp Oil remedies. Proponents of Hemp Oil suggest that it may help with feelings of nervousness, anxiety, improved sleep and reduced pain.

The discoveries will continue to come. Each new finding will help our scientists complete this elusive puzzle and get us one step closer to a solution. The cure is out there. In the meantime, we can do what we can to reduce the rate of damage to our nerve cells. We can improve our exercise routine, our supplement intake, and our spiritual world. Choose to live your best life. Stay strong!

Pena, PhD., Ana. “Energy Demands to Counter Gravity in Vertical Neurons May Lie at Origin of ALS”, ALS NEWS TODAY, August 30th, 2019.

These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.

The Nutritional Supplement approach to ALS!

A natural and cost-effective alternative.

supplements for als

It is widely understood by the ALS community that there are limited solutions for the treatment of this devastating disease. The widely varying progression from patient to patient makes it difficult to standardize the appropriate approach. Not enough information is known and not enough research has been done. Pharmaceutical drugs are costly, cumbersome, and the benefits are often marginal.

An alternative approach to pharmaceuticals (or even an additional approach to pharmaceuticals), is to ensure that the body has the essential supplements for ALS and nutrients that it needs to help protect against the progress of this disease and to also provide much needed energy to the cells. Often, the worst case scenario with supplementation is that nothing perceivable happens, or that there are very mild side-effects from taking these supplements, many of which already occur naturally in the body. The best case scenario, however, can be delayed disease progression, reduced severity of the symptoms, and an overall improved quality of life.

The Deanna Protocol (DP), created by Dr. Vincent Tedone, is one such approach. This Protocol was initially based on Dr. Tedone’s research with his daughter, Deanna, who was diagnosed with ALS nearly 10 years ago. According to Dr. Tedone, the DP works because it provides two primary mechanisms of action. The first, is that it provides the body with the nutritional supplementation it needs and that allows the body to properly metabolize and remove excess glutamate, the leading cause of nerve cell death. The second mechanism, is that the DP provides nerve cells (neurons) with additional energy that help keep the neurons healthy and functioning for longer.

The Deanna Protocol consists primarily of the following naturally occurring supplements:

AAKG and AKG (Arganine Alpha Ketoglutarate)
AKG is the key supplement providing energy to the cells and is required by the body to keep cells alive. The Arganine in AAKG improves the palate of the AKG and makes it easier on the stomach. Arganine also produces the free radical, nitrous oxide (NO). The NO can increase blood flow, which possibly assists in the removal of excess glutamate in the blood stream. Excess glutamate is the cause of cellular death in ALS. Those with preexisting heart conditions should consult with their physician before consuming arginine.

Ubiquinol (CoQ10) helps the energy cycle in mitochondria and is known for its antioxidant properties. Oxidative stress and mitochondrial dysfunction have been implicated in the pathophysiology of ALS. CoQ10 also promotes energy and overall vitality and helps normalize circulation.

Niacin and 5-hydroxytryptophane are precursors to NADH, which is unable to be absorbed by the GI system. NADH is essential in several of the reactions of the energy cycle and is also important in transporting electrons.

GABA is an inhibitory neurotransmitter. In patients with ALS, excitatory and inhibitory neurotransmitters are out of balance, which necessitates the addition of GABA. This balance of neurotransmitters reduces anxiety and rigidity of the muscles.

Glutathione is critically important for detoxification. With its anti-inflammatory properties, it’s considered one of the most important antioxidants in the healthy functioning of cells. The body uses glutathione to protect against toxins. Cells deficient in glutathione have difficulty defending against toxins in food, pollution, radiation, carcinogens, heavy metals, and drugs.

These supplements for ALS, when combined in the appropriate doses and quantities as provided by Simplesa Nutrition, can detox the body and may improve mobility, reduce pain, increase energy, and a plethora of other health benefits. It’s often up to you, the patient with ALS, in association with your doctor, to determine the best treatment protocol or combination of protocols that works best for you. Consider nutritional supplements as an additional support in your fight against neurodegenerative diseases.

1.    Tedone M.D., V.M., Tedone-Gage, D., & Tedone, C. The Deanna Protocol Hope for ALS and Other Neurological Conditions. Tampa: Paradies/ Inspire, LLC, 2015. Print.
2.    ALS News Today: To ‘B’ or Not to ‘B’?. July 25, 2018 by Rick Jobus
These statements have not been evaluated by the FDA. These products are not intended to diagnose, treat, cure or prevent any disease.